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In this review, we summarize and discuss the relationship between carnitine and NAFLD, effects of L-carnitine (the biologically active form of carnitine) supplementation in NAFLD, and related diseases, including non-alcoholic steatohepatitis (NASH), cirrhosis, hepatic cellular cancer (HCC), alcoholic fatty liver disease, and viral hepatitis

After analyzing 31 polymorphisms in 11 genes, it has been discovered that in presence of the C allele in SLC22A4 (OCTN1 rs1050152), and the two minor alleles (G) in SLC22A5 (OCTN2 rs2631367 and rs2631372) the time to progression was significantly improved ( General Features of OCTN1 (SLC22A4) and Implications in Cancer Organic cation transporter OCTN1 is another member of the SLC22 family

composition as described hereinabove may be administered as a drug either orally or by injection