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Description
Without treatment, pellagra can be fatal, which is an important factor to be considered, since its low prevalence in developed countries causes missed diagnosis and delayed treatments (, , , )
282,283 Several natural phytochemicals, such as curcumin, have also been shown to inhibit NF-B nuclear translocation while simultaneously activating Nrf2, an antioxidative pathway
Furthermore, it has been demonstrated that lipid peroxidation products have carcinogenic and mutagenic qualities (116)
Early intervention significantly improves outcomes and can prevent irreversible nerve damage
