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Succinyl-CoA is oxidized to fumarate by the succinate dehydrogenase (SDH) complex and then hydrated to malate by fumarate hydratase (FH)

Safety and efficacy of cognitive training plus epigallocatechin-3-gallate in young adults with Downs syndrome (TESDAD): a double-blind, randomised, placebo-controlled, phase 2 trial

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5,7 In this review, we focus on these immune populations, detailing how aging compromises their differentiation and functional capacity, while their dysregulation reciprocally accelerates the senescence process