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Lorsqu'il est utilis de manire responsable cycles courts (4 6 semaines) , IGF-1 LR3 est considr sr avec des effets secondaires minimes Cependant, une utilisation prolonge au-del des protocoles recommands peut entraner une dsensibilisation des rcepteurs ou un dsquilibre des niveaux dhormones naturelles

However, numerous studies, both early and recent, have demonstrated that HIF-1 can remain stable even under normoxic conditions

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"Extracorporeal Shock Wave Therapy for Chronic Painful Heel Syndrome: A Prospective, Double-Blind, Randomized Trial." Journal of Bone and Joint Surgery , 2007