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Impaired FAD-dependent enzyme activity is also detrimental to bloodbrain barrier (BBB) integrity, leading to downregulation of tight-junction proteins such as claudin-5 and occluding, increased permeability, and enhanced peripheral immune infiltration

Sensors 21(1):120 Krauss JK, Lipsman N, Aziz T et al (2021) Technology of deep brain stimulation: current status and future directions

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