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Adipocytederived extracellular vesicles modulate appetite and weight through mTOR signalling in the hypothalamus

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In the catalytic hydrolysis of glutamine, Ser286 at the active site of the GLS1 enzyme carries out a nucleophilic attack on the acyl carbon of glutamine, and the subsequent proton transfer of Tyr466 promotes the hydrolysis reaction

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Together, BPC-157 + TB-500 create a synergistic regenerative effect, targeting both structural repair (BPC-157) and cellular dynamics/angiogenesis (TB-500)

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