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In healthy adult subjects, single subcutaneous doses of CJC1295 led to a 2 to 10fold rise in GH for six days or more and a 1.5 to 3fold increase in IGF1 that persisted for 911 days
Paraquat resistance assay Adult wt worms were allowed to lay eggs on LB or DB NGM plates
We further examined the impact of this treatment combination on food intake and body weight and used molecular experiments in attempts to define underlying mechanisms
The implications for treatment are profound, with ongoing research exploring how to manipulate ROS for better outcomes
