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The ability GSHee to suppress fentanyl-induced disordered (non-eupneic) breathing raises the possibility that GSH-dependent mechanisms in key brainstem sites responsible for the control of breathing may be recruited to prevent the negative effects of fentanyl on eupneic breathing

These effects usually resolve within the first week of use as the body adapts to the peptide

Consistent timing helps establish steady-state levels

It was shown in 1976 in Sendai virus, the proteins used to bind and subsequently fuse the virus to the host cell are glycoproteins that present as oligomers connected with Inter-peptide disulfide bonds