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Systemic and metabolic conditions such as diabetes, obesity, multiple sclerosis, rheumatoid arthritis, lupus erythematosus, ankylosing spondylitis, as well as Alzheimers disease, Parkinsons disease, chronic depression and autism spectrum disorders also become a growing health problem [1,2,3,4,5,6]
As mentioned above, chewing cruciferous vegetables such as broccoli makes GRP available for plant myrosinase causing the conversion of GRP to SFN and/or SFN-nitrile in the oral cavity ( FIGURE 2 Microbiota-produced GRP metabolites are absorbed in the intestine and transported with blood to various organs, including the liver, and partially excreted with feces
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