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Elevation of intracellular Ca 2+ activates scramblase to ensure PS externalization, opens the Gardos channels, resulting in K + efflux and subsequent cell shrinkage, and mobilizes calpain, leading to cytoskeleton degradation and membrane microvesiculation [78]

Bors, L

type II spiral ganglion neurons exhibit differential survival and neuritogenesis during cochlear development

Many patients may feel the improvement of symptoms after taking medication but are not satisfactory with the overall effect while some patients may be getting even worse (50)
