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In order to confirm that the phosphorylation of T432 is critical for ATF3-mediated ATM activation upon IR, we transfected the wild-type PXR or the PXR T432A mutant plasmid into the PXR-KO LS180 cells and then subjected cells to IR

Epithelialmesenchymal transition (EMT) beyond EGFR mutations per se is a common mechanism for acquired resistance to EGFR TKI

[DOI] [PubMed] [Google Scholar] [63].Wu Y, Zhang Y, Zhang W, et al
FEBS Lett 589:26612667
