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For superoxide anion, the main ROS, a first line of defense is represented by the enzyme superoxide dismutase, localized in the mitochondrial matrix
[DOI] [PubMed] [Google Scholar] 635
The first day of the 2 protocols was considered an adjustment period, and included the patients history and physical, blood work, and baseline studies
Accordingly, physicians should consider other treatment regimens to improve these symptoms, which might impact patients' quality of life with PD
