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Moreover, its shortcomings have been linked to disturbed homocysteine metabolism, which is associated with various conditions including cancer and cardiovascular disease [52, 53]

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Niacinamide supports the barrier function of the skin by increasing the lipid and protein stratum corneum

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Additionally, vitamin B12 deficiency can cause neurocognitive manifestations including depression, episodes of psychosis, delirium, dementia, poor memory performance, and cognitive impairment (, , )

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