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It is known to exacerbate inflammation and redox imbalances (251) by triggering the NLR family pyrin domain containing 3 (NLRP3) inflammasome (251), increasing the release of inflammatory cytokines such as IL-1 and IL-18 (376)

Thymosin Beta-4 (Injection) Promotes cell migration and tissue regeneration, reducing inflammation and accelerating wound healing

Cell culture The following cell lines were used in this study: IMR90 and WI-38 human fetal lung fibroblasts (female), BJ human foreskin fibroblasts (male), NIH3T3 mouse fibroblasts, wt and bax/bak / littermate Baby Mouse Kidney (BMK) cells, Human Embryonic Kidney (HEK) 293LTV