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This key effect of GSHee is connected to the findings that GSHee reduced the ability of fentanyl to lower pH, pO 2 and sO 2 while elevating pCO 2 (all consistent with a fall in Ve) and blunted the fentanyl-induced increase A-a-gradient (i.e., impaired gas-exchange in the lungs)
The typical dosage ranges from 200 to 300 micrograms per injection, administered subcutaneously using an insulin syringe
