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Description
Relevant to the above cases, High dose FA can improve BH4 recycling due to restoration of dihdrofolate reductase expression [35]

reported that HIF-1 and HIF-2 mRNA were overexpressed in segments of rat IVC exposed to prolonged 2-g tension and that the overexpression was reversed by the HIF inhibitor U0126 [91]

Recent advances in artificial intelligent strategies for tissue engineering and regenerative medicine
discussion 159-163, 211-158
