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& Johansson, M

Thiol groups are important components of redox-mediated processes due to their unique chemistry, involving nucleophilicity, metal binding, and the ability to form protein disulfide bonds (Ulrich and Jakob, 2019)

In renal tubular epithelial cells treated with calcium oxalate (CaOx) to induce kidney stone formation, CHAC1 expression increases alongside a decreased GSH level, reduced GPX4 activity, increased iron and MDA content and elevated ROS and lipid peroxidation

Mol Biol (Mosk) 47:591601 Lo Cicero L, Madesis P, Tsaftaris A, Lo Piero AR (2015) Tobacco plants over-expressing the sweet orange tau glutathione transferases (CsGSTUs) acquire tolerance to the diphenyl ether herbicide fluorodifen and to salt and drought stresses