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Description
Essentially, the lack of modern data proving it doesnt happen is the reason for the restriction
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It is produced using peptide synthesis methods and characterized through analytical techniques such as HPLC for purity and MS for mass confirmation

doi: 10.1177/17590914211010647 46 SaulDGleitzSNguyenHHKosinskyRLSehmischSHoffmannDBet al

His-F8 of the myoglobin, also known as the proximal histidine, is covalently bonded to the 5th coordination position of the iron
