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Its mechanisms include modulation of neurotransmitter signaling that promotes slow-wave activity, reduction of nighttime cortisol and stress hormone interference with sleep architecture, and support for the timing and depth of the sleep cycle itself

Finally, the analysis showed colchicine caused a higher rate of gastrointestinal side effects, but not serious adverse side effects, than control

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found that active GSH metabolism within tumors further suppresses immune responses, such as IFN- signaling and PD-1/PD-L1 interactions, while reducing the number of M1 macrophages and increasing the proportion of M2 macrophages