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These adaptations reflect neuroplastic remodeling of pain circuits rather than restoration of tissue integrity

Our conclusions will both relate to and can have profound implications for disease prognosis
The body eliminates alcohol at a steady rate: about one standard drink per hour

Supporting this hypothesis, a chronic unpredictable mild stress mouse model demonstrated that melatonin effectively restored aquaporin-4 polarization and rectified the compromised glymphatic system observed in this model [215]
