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The San-Huang-Yi-Shen capsule (SHYS) significantly reduces Fe 2 levels while enhancing SLC7A11, GPX4, and GSH/GSSG levels, providing renal protection in diabetic nephropathy models [98]

Archived from the original on May 9, 2019

The use of -endorphin knock-out mice confirmed a causal link between MOR phosphorylation by this peptide and reduced responsiveness to exogenous ligands since sciatic nerve ligature in knock-out animals failed to produce both [10]
