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FIGURE 4 Potential Role of Chronic Physical Exercise on Immune System Modulation: Implications on Vitiligo Development It has been well established that structured chronic PE has an anti-inflammatory effect ( + T cells to melanocytes and to start the process of destruction of these cells (Rashighi et al., 2014)

Biomed Res 30:149156 Tolhurst G et al (2012) Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2

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