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Description
This can be achieved through random mutation using chemical mutagenesis or a gene trap approach, or through gene targeting to generate a knockout mouse
Wawrzyska and Sirko, 2014
[DOI] [PubMed] [Google Scholar] 230.Jones D, et al
Targeting the APOE 4 allele or inhibiting TREM2 in microglia, leads to clearance of A, decreasing the inflammation of the nervous system, and slowing AD progression (102)
