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Published safety data from clinical trials report no significant adverse effects across all studied doses and durations

doi:10.1007/s00216-007-1271-6

[DOI] [PMC free article] [PubMed] [Google Scholar] 43.Ramsey KM, Mills KF, Satoh A, Imai S
Rebound effects occur once the alcohol has been largely metabolized, causing late night disruptions in sleep maintenance