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In another study to address this same question of the necessity of having Tyr10 present in A42 for oxidative damage and neurotoxicity, we examined the short peptide A116, which has all three His residues to which Cu 2+ would bind as well as Tyr10 (115)
doi:10.1016/j.jbior.2012.09.008
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There is a chance that peptides besides GLP-1s will eventually be demonstrated to provide health outcome benefits as seen in rodent pre-clinical models