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Description
Development of methods and research should be conducted to assess the endogenous occurrence of hydroxyethylation and the exogenous (environmental) contribution of ethylene oxide and its precursors to the formation of macromolecular adducts as markers of internal dose

This simple method was shown to be reproducible and effective
Zhang XQ
Figure 2 describes the relationship of the onset rate to LOCINDTI (the acceleration onset rate curve)