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This effects complexity (distinct NO-response patterns) includes their distinctive relationships, requiring the investigation of NO-system function as a whole, with all of its particularities, to realize the BPC 157/NO-system relationship [11,29]

Nitric Oxide Synthesis and Function Vasodilators, such as acetylcholine, bradykinin, and adenosine do not exert their effects upon the vascular smooth muscle cells in the absence of the overlying endothelium