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Description
Uncontrolled Hypothyroidism: An underactive thyroid must be managed before starting sermorelin

doi:10.1111/cea.13880

This release can occur through different mechanisms, such as nanoparticle dissolutionan instability that arises under specific pH conditions, typically at lower pH, leading to matrix dissolutionand polymer swelling, a process in which nanoparticles swell at certain pH conditions, both ultimately resulting in drug release (Karimi et al., 2016)

Rats and mice were anesthetized with 2.5% isoflurane
