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Description
DREADDs could couple via the Gq or Gi pathways to stimulate or inhibit neuronal activity, respectively
Due to insufficient blood supply, rapidly growing tumors in vivo are often hypoxic, and it is conceivable that this could enhance the therapeutic efficacy of APR-246, both in wild type and mutant TP53-carrying tumors
Huang F, Wang J, Xu Y, Zhang Y, Xu N, Yin L (2020) Discovery of novel isoliquiritigenin analogue ISL-17 as a potential anti-gastric cancer agent
Left untreated, a severe deficiency can cause permanent nerve damage
