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Furthermore, we assigned the PLS2+/ genes to seven distinct brain cell types compiled from previous studies to examine their cellular specificity in the nervous system

wet AMD is the most severe form and is characterized by the growth of abnormal choroidal vessels and leakage of blood and fluid (2, 3)

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Lipotoxic ER stress also contributes to IR, which was mechanistically associated with the lipotoxic inhibition of IRE1 and its downstream transcription factor XBP1 via Bax inhibitor-1 (BI-1), an ER membrane protein [63]