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In humans, LECs present in the LNs can be categorized into 6 subsets: (1) SCS ceiling LECs (LECs I in human, cLECs in mouse), (2) SCS floor LECs (LECs II in human, fLECs in mouse), (3) medullary capsule-lining LECs (LECs III in human), (4) paracortical sinus LECs (LECs IV in human, Ptx3-LECs in mouse), (5) Valve LECs (LECs V in human) and (6) medullary sinus LECs (LECs VI in human, Marco-LECs in mouse) (58, 68) ( Figure 2 )

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D-fenfluramine-induced prolactin and cortisol release in major depression: response to treatment