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JNK is involved in the regulation of inflammation and cell death, with both pro- and antiapoptotic reported functions (198, 291)

A two-sided p-value below 0.05 was considered statistically significant

Via the STAT3/GPX4 pathway, Thiostrepton (TST) induces ferroptosis in pancreatic cancer cells by reducing cellular iron overload, increasing ROS accumulation, raising MDA levels, and decreasing GSH-PX in these cells [138]

A good candidate for self-injection is someone who is medically stable, has no bleeding disorder, is not on high-dose blood thinners without medical guidance, has completed an in-clinic training session, and has a reliable sharps container at home