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Furthermore, Rhein might change purine metabolism and induce an alteration in the composition of the gut microbiota, which was sufficient to relieve DSS-induced colonic damage
Scientists have found low NAD+ levels in patients with Alzheimer's, Parkinson's, and multiple sclerosis

IGF-1 has plaque-stabilizing effects in atherosclerosis by altering vascular smooth muscle cell phenotype

Practice Bulletin, 196, 1-18
