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Activated IGF-1R phosphorylates insulin receptor substrate proteins (IRS-1 and IRS-2), which recruit and activate PI3K
7e, f), while neuronal GABA levels, although slightly elevated, remained unaffected by KDS2010 (Supplementary Fig
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MR can reduce H3K4me3, H3K9me2, H3K27me3, and H3K36me3 methylation, enhancing the drug sensitivity of lung cancer cells (46)
