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Description
Neurotoxicol 2021, 5, 239262
Intrathecal administration ensures that tofersen targets motor neurons with pinpoint accuracy through cerebrospinal fluid, effectively diminishing cerebrospinal levels of SOD1 protein and plasma levels of neurofilament light chainsbiomarkers that signal the regression of neuronal damage (43)
The metS + RAS group exhibited higher levels of RIPK1 and RIPK3, but the EV from MSC decreased these levels (285)
(PubMed) Berry MJ, Banu L, Harney JW, Larsen PR
