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A number of studies have shown that a malfunction/degradation of mtDNA is associated with a variety of age-related diseases, including Alzheimers disease, macular degeneration, and cancer [79,80,81]

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In addition, MOR and DOR recycling may be dynamically regulated through receptor phosphorylation [46, 60] and interactions with arrestin1 and arrestin2 [61]

Urinalysis may help differentiate between renal and prerenal azotemia