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SAC can effectively alleviate UC, which is based on SAC elevating the expression of antioxidant enzymes like GPX4 and NQO1, while reducing ROS and MDA levels

Participanii au fost tratai cu L-Carnitin timp de 12 luni, iar rezultatele au artat o mbuntire semnificativ a funciei cardiace i o reducere a simptomelor anginei

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Using HD mouse and cell models, we demonstrated that TFEB and TFE3 are sequestered in muHTT aggregates, and muHTT proteins associates with LMP triggering the translocation of LGALS3 to the lumen of lysosomes, with a close relation between polyQ size and severity of these events
