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Lipoxygenase/Leukotriene Pathway Activation of 5-lipoxygenase (LOX) in ( primarily expressed in leukocytes ) results in the conversion of arachidonic acid to leukotrienes that function as inflammatory mediators (Wikipedia) resulting in: bronchoconstriction increased secretion of mucus leukocyte chemotaxis histamine release This pathway has its greatest clinical relevance in the pathophysiology of asthma
Even if both are the same concentration, combining them introduces unnecessary contamination risk and makes tracking the 28-day expiration window impossible
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doi: 10.1093/jn/128.4.707
