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During the stress response, this Ca 2+ concertation gradually increases within the cytosol by coming down the concentration gradient from the apoplast or vacuolar storage

FIGURE 34 Blood concentration-time curves, illustrating how changes in the rate of absorption and extent of bioavailability can influence both the duration of action and the effectiveness of the same total dose of a drug administered in three different formulations

doi:10.7759/cureus.26103

& Wilson, J
