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Previous metabolomics studies have reported LID-specific alterations of glycerophospholipids and endocannabinoid signalling in dyskinetic rodent models 20 and significant dysregulation in glycosphingolipid metabolism in plasma and cerebrospinal fluid (CSF) samples from LID patients, correlating closely with the severity of dyskinetic movements 21

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[DOI] [PubMed] [Google Scholar] 283.Cegelski L., Pinkner J.S., Hammer N.D., Cusumano C.K., Hung C.S., Chorell E., Aberg V., Walker J.N., Seed P.C., Almqvist F., et al