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Kwon and Park 2015 reported that intra-articular AOD-9604 injections, especially when combined with hyaluronic acid, improved cartilage scores and reduced lameness in a rabbit collagenase-induced osteoarthritis model

Both authors contributed to the article and approved the submitted version

Repeat up to 3 times weekly
Additionally, trehaloses anti-inflammatory properties augment the benefits of HA
