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IN GHK-Cu improved escape latency across Trials 2-4 in both sexes ( P 0.05) (Figure 1C-D)
Prx3 is the Prx isoform exclusively located in mitochondria, suggesting that it plays a primary line of defense against H 2 O 2 produced by the mitochondrial respiratory chain
This is potentially due to the formation of inhibitory fragments by brush-border enzymatic degradation of LA during the ex vivo recovery process
This finding indicates that even in the context of inhibiting tumor growth, anthraquinone compounds can still induce protective autophagy in tumor cells
