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At the mechanistic level, the hypothesized link between NSW and BC is grounded in the concept of circadian disruption 12

The Blood-Brain Barrier in Systemic Inflammation

Acknowledgements This work was supported by a National Health and Medical Research Council (NHMRC) of Australia Centres for Research Excellence Grant #1040947 (W.A.P.), a Translational Research Project Grant (TRP15012) from the Victorian Government Department of Health and Human Services through the Victorian Cancer Agency (W.A.P., N.J.C., C.P.D.), and a Peter MacCallum Cancer Foundation New Investigator grant (D.S.L.)

Five distinct GPx isozymes have been characterized in mammals, (Table 1) [12]
