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Its smart to keep an eye on B12 levels to adjust treatment as needed

In addition to migraine-related CSD, brief needling of the frontal cortex has been shown to induce CSD, resulting in a sustained increase in cerebral metabolic rate of oxygen and a decrease in basal cerebral blood flow (12)

[DOI] [PMC free article] [PubMed] [Google Scholar] 67.Peng L, Agogo GO, Guo J, et al

Mitochondria-targeted analogues of metformin exhibit enhanced antiproliferative and radiosensitizing effects in pancreatic cancer cells
