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We also discuss the limitations and criticisms of the paper, including questions around causality, alternative explanations, and the extent to which pharmacogenetics alone can account for the outcome

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Although PEGylated SOD (PEG-SOD) increases the enzymes stability in the circulation from 6 min to 36 h, PEG limits the permeability of the conjugated SOD across cerebral cell membranes [335]

Ketorolac tromethamine is contraindicated in labor and delivery because, through its prostaglandin synthesis inhibitory effect, it may adversely affect fetal circulation and inhibit uterine musculature, thus increasing the risk of uterine hemorrhage