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lysosomes remained intact, demonstrating selectivity of organelle targeting In vivo tumour eradication pre-clinical studies have reported tumour eradication in nude mouse xenograft models following PNC-27 treatment Ovarian cancer models intraperitoneal mouse toxicity and maximum tolerated dose studies conducted alongside ex-vivo testing against primary patient-derived epithelial ovarian cancer cultures, demonstrating dose-dependent cytotoxicity including activity against chemotherapy-resistant ovarian cancer lines Haematological malignancy models near-complete cancer cell death reported in leukaemia models, including p53-deficient cells, via HDM-2 membrane binding Cervical cancer models confirmed selective killing of cervical cancer cells with no effect on untransformed cervical cells

Side effects Pain and swelling at Injection site Skin rash Itching Swelling Muscle cramps Weakness Dizziness Difficulty in breathing Diarrhoea Headache Precautions and Warnings Pregnancy Breast Feeding Driving Alcohol Other General Warnings You have any existing medical condition like diabetes, hypertension, kidney or liver problem