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MRP2 is responsible for mediating the excretion of organic anions and drug metabolites, while BSEP is responsible for the excretion of bile acids (Wang P

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This is maintained by balance in the production of free radicals and antioxidants

Cecal levels of Erysipelatoclostridium abundance have been positively correlated with dyslipidemia 93 , and a report that WD decreased the relative abundance of Erysipelatoclostridium and that the abundance of Erysipelatoclostridium negatively correlated with obesity-related indices 90 may partially explain our observation that decreased levels of Erysipelatoclostridium were present in the 5A-1MQ-treated group and the WD control group relative to the vehicle-treated group switched from WD to LD