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Furthermore, Talay et al [56] have shown that proactive, personalized lifestyle coaching design significantly enhances patient engagement in semaglutide-supported programs, while another study by Talay et al [57] highlights the robust efficacy of tirzepatide-supported digital interventions [58]

Pharmacologic models can then be used to calculate the albumin affinity of the test compound

In a sodium monoiodoacetateinduced model of osteoarthritis, a single intra-articular injection of 20 g liraglutide reduced pain sensitivity and synovitis, in the absence of any changes in body weight (86)

Acknowledgments This work was funded by the Commonwealth Fund