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Wichtig ist die Unterscheidung der CJC-Varianten
These metabolites also stimulate expression of ferritin, which stores iron within enterocytes and limits its availability for export from enterocytes, ultimately returning iron to the gut when the enterocytes are sloughed
Additionally, a current phase 2 clinical trial is evaluating the safety and efficacy of SAR442970 a bsAb targeting both TNF- and OX40L in preserving pancreatic -cell function in individuals recently diagnosed with T1D (NCT06812988)
doi: 10.1126/science.aat5314 418 PoonDCHoYSChiuKWongHLChangRC
