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However, I mention them because nearly all modern studies do also, suggesting they are still of clinical relevance

[149] Derived from Table 2 available on [150] History [edit] Between 1849 and 1887, Thomas Addison described a case of pernicious anemia, William Osler and William Gardner first described a case of neuropathy, Hayem described large red cells in the peripheral blood in this condition, which he called "giant blood corpuscles" (now called macrocytes), Paul Ehrlich identified megaloblasts in the bone marrow, and Ludwig Lichtheim described a case of myelopathy

This helps researchers move from compound-specific review into broader pathway comparison without leaving the core research archive

Think of the peptide as the vehicle and the copper as the critical passenger it delivers to cells